According to the ESRB, this game contains: Mild Language, Partial Nudity, Use of Alcohol, Violence
Parents could do a lot worse than let teenagers play this game. Bad language is frequent but mild; the worst word in Suikoden V is "bastard." There are big-breasted women, jokes about men and women bathing together and one (silly) instance of cross-dressing, but the violence isn't bloody at all.
Loading time haters will find plenty to disgust them, unfortunately. The game needs to load after every battle—and there are a lot of random encounters.
Gamers who like killing things will have to wait a good 6-8 hours for the action to start. Until then, players do lots of running from one place to another and back, but not much fighting.
Deaf and hard of hearing gamers should have no problems. All in-game speech is subtitled and there are no significant auditory cues.