According to ESRB, this game contains: Blood, Crude Humor, Mild Language, Mild Suggestive Themes, Use of Alcohol and Tobacco, Violence
Parents should not be too concerned, in my opinion. Although the rating seems like a litany of evils, I didn't think the game seemed very crude, and the worst language I can recall is "damn." The level of violence isn't worse than many modern cartoons, and there are a couple of notable death scenes that are more about emotional investment than any kind of bloodbath. In short, kids are going to be exposed to far more negative influences than this game, whether on television or while at school.
RPG fans should definitely give this action-packed, color-laden game a romp. It is full of flair and imagination, and unless adverse to action (versus turn-based), I don't think these gamers should miss it.
Voice-acting critics ought to be impressed. The performances are all top-notch. Plus, the game features Michell Ruff, who I feel is a quite talented voice performer.
Deaf and Hard of Hearing gamers should be fine: all dialog is accompanied by text, so the story won't lose any nuances. There is nothing audio-specific about the gameplay.