According to ESRB, this game contains: Blood, Mild Language and Mild Violence
Parents shouldn't be too concerned. Naturally there's a bit of blood since this IS a surgery game, and you can't really operate without seeing some red stuff. I can't really figure out what the violence is since I don't think the operations count, and there's only one brief scene in the whole game that features a small altercation, it's all of two frames and nobody even gets shot. The language is negligible… not anything even worth mentioning. I suppose the ESRB is getting highly sensitive these days and erring on the side of over-caution. It's a hard game, but nothing that will corrupt your kids. They may even learn something from it what with all the medical terms and talk of responsibility.
Wii Gamers, just go buy it. If you own a Wii for the sake of new experiences and innovative gameplay and you haven't tried this on the DS for some crazy reason, here you go… it's a perfect example of how the Wiimote and Nunchuk should be used. ‘Nuff said.
Deaf and Hard of Hearing gamers get full text for all conversation in-game. However, during tense procedures it's sometimes easier to hear when something happens than to visually try and see it. For example, when a patient's life drops into the danger zone an audio cue is given, but without hearing a player would have to take their eyes off the action to look at a life bar at the top of the screen. A small effort, but sometimes a second can make all the difference. Still, I'd say that it's equally accessible in the vast majority of play.