According to ESRB, this game contains: Blood, Violence
Parents don't have much to worry about. There's murder and villainy, and a little bit of blood, but the movie was PG-13, and the game is definitely less gruesome.
Da Vinci Code fans should check the game out. It's better than the film or book, and an easy enough game that non-gamers will be able to play it without too much trouble.
Da Vinci Code foes be warned—the game is good enough that it may just win you over, so play at your own risk.
Deaf and Hard of Hearing gamers will be mostly okay. The game is entirely subtitled, but there are a few situations where being able to hear footsteps would definitely be an advantage.