According to the ESRB, this game contains: Blood, Language, Use of Alcohol and Tobacco, Violence
Parents should probably be careful about letting young children play this one. There's a stone that gets its power from human blood and a teenage boy with a chip on his shoulder and an expansive vocabulary. ("You bleepity-bleep BEEPs!") No one ever veers into s- or f-word territory, however.
Gamers who like strong stories and interesting characters will have plenty to like in Fullmetal Alchemist 2. While the story isn't as complex as some other Square-Enix RPGs that shall remain nameless, it's well-plotted and the interactions between Ed and Al Elric are always fun to watch.
Interested parties who haven't seen the Fullmetal Alchemist anime should give Curse of the Crimson Elixir a shot. Though I wasn't very familiar with the anime before playing it, I could easily follow the story. In fact, I liked the story so much that I started watching Fullmetal Alchemist.
Deaf and Hard of Hearing gamers get partially forgotten by Square Enix, unfortunately. While the in-game dialogue has captions, the cutscenes ("movies") that come directly from the anime do not. Other than this problem, there aren't any significant auditory cues.