According to the ESRB, this game contains: Alcohol Reference, Mild Language, Simulated Gambling, Violence
Parents will want to exercise caution. The game is about fighting and physical violence (naturally), so make sure the subject is all right before purchase. Some characters are shown in a bar, making up the alcohol reference noted on the back of the box. The gambling highlighted is when the player places a bet on the outcome of each fight. Personally, I saw this as mathematics strategy and not necessarily something that could be completely classified as classical gambling, but be aware that it's in here. I did not notice the mild language, and there are no sexual situations although it is worth noting that some characters are dressed somewhat provocatively and scantily-clad characters can be created if they are so desired. Overall, I would say that this game is definitely more appropriate for teenagers and adults than young ones.
Fighting game fans will be in for a treat. This game breaks away from conventions in just about every area by featuring a combat engine that is like a mix of boxing and street fighting. The over-the-shoulder camera is great, and most of the fights are three-on-three team affairs, although the matches play out one-on-one. Also, it's worth noting that the game takes a lot longer to beat than the average fighting game. You definitely won't see credits in the first couple days, so prepare yourself for a substantial playtime that deals with stats and making money.
Deaf and Hard of Hearing gamers will want to know that the game features no subtitles for any of the cutscenes. These scenes are short and very few in number, but it's still disappointing. However, there are no significant auditory cues during gameplay and most of the cutscenes are pretty worthless to begin with, so although it would have been nice to have subtitles, the game is still quite playable. Personally, I played about half the game without any sound whatsoever and had no problems besides the cutscenes.