According to the ESRB, this game contains: Blood, Violence
Parents, your kids are about as safe with this game as they are with just about any other fighter out there. I honestly don't see how it rates an M, since the only difference to my eye is that some of the moves cause copious blood to flow, although it remains as unrealistically over-the-top as most of these games are. There is neither questionable language nor any sexual content.
Fighting game fans should probably look elsewhere. The game meets the standard requirements, but does little more. With a number of other choices available on shelves, your money is better spent elsewhere, not to mention the fact that you can buy an older version from this same series and get nearly the same experience.
Deaf and Hard of Hearing gamers will have no problems. Subtitles are available for all of the in-game speech, and there are no significant auditory gameplay cues.