According to ESRB, this game contains: Comic Mischief, Mild Language, Violence
Parents should have no trouble with this game. If their kids have been wanting Grand Theft Auto, but they've felt uncomfortable with the violence, this makes a perfectly acceptable substitute. (The kids will probable still want GTA though.)
New fans of the show might enjoy this as a crash course in Simpsons trivia, as it gathers its references from the entire run of the series.
Die-hard fans of the "Classic" Simpsons should stay away, as its repetitive, obvious humor will become depressing rather quickly.
Deaf and Hard of Hearing gamers are in for a mixed bag. While the vital information (where to go, what to do) is mostly provided as text onscreen, absolutely none of the "wacky" character dialogue is, and that dialogue is the game's main selling point.